Comparative Effectiveness Research through Collaborative Electronic Reporting

222 Practicing Sites
27 States
2119 Pediatricians and nurse practitioners
>2 Million Covered Lives
...and growing!

Interested in proposing a project using the CER²dataset?

Please contact Jenny Steffes, MSW at (630) 626-6537 or jsteffes@aap.org.

Examples of Studies

Pediatric Hypertension
ADHD diagnosis and prescribing
Patterns of prescribing for psychotropic mediactions
Prescribing patterns and safety profile of antipsychotics risperidone and aripiprazole
Benchmarking antibiotic use to inform outpatient stewardship

PROS/CER² is supported by:

The American Academy of Pediatrics
The Health Resources and Services Administration (HRSA) of the U.S. Department of Health and Human Services (HHS) under grant number (UA6MC15585) and title (MCH Research Network Programs). Information or content and conclusions are those of the author(s) and should not be construed as the official position or policy of, nor should any endorsements be inferred by HRSA, HHS, or the US Government.
Past support for CER2 from the Health Resources and Services Administration Maternal and Child Health Bureau:

UB5MC20286 “Pediatric Primary Care EHR Network for CER”
R40MC24943 "Primary Care Drug Therapeutics CER in a Pediatric EHR Network,"

Publications

Gabryszewski J, Dudley J, Shu D, et al. Patterns in the Development of Pediatric Allergy. Pediatrics 2023; e2022060531. doi:10.1542/peds.2022-06053.

Kaelber DC, Localio AR, Ross M, et al. Persistent Hypertension in Children and Adolescents: A 6-Year Cohort Study. Pediatrics. 2020;146(4):e20193778 doi:10.1542/peds.2019-3778

Gregory EF, Miller JM, Wasserman RC, et al. Adherence to Pediatric Universal Cholesterol Testing Guidelines Across Body Mass Index Categories: A CER2 Cohort Study. Circ Cardiovasc Qual Outcomes. August 2020; doi:10.1161/CIRCOUTCOMES.119.006519

Kaelber DC, Localio AR, Ross M, et al. Persistent Hypertension in Children and Adolescents: A 6-Year Cohort Study. Pediatrics. 2020;146(4):e20193778 doi:10.1542/peds.2019-3778

Czaja A, Ross ME, Liu W, Fiks AG, Localio A, Wasserman RC, Grundmeier R, Adams WG. Electronic health record (EHR) based post-marketing surveillance of adverse events associated with pediatric off-label medication use: a case study of short-acting beta-2-agonists and arrhythmias. Pharmacoepidemiology and Drug Safety. 2018;1‐8. https://doi.org/10.1002/pds.4562

Daymont C, Ross ME, Localio R, Fiks AG, Wasserman RC, Grundmeier RW. Automated identification of implausible values in growth data from pediatric electronic health records. J Am Med Inform Assoc. 2017:24(6) 1080-1087. DOI: 10.1093/jamia/ocx037.

Czaja A, Fiks AG, Wasserman RC, Valuck RJ. Beyond the Label: Steering the Focus Towards Safe and Effective Prescribing. Pediatrics. Apr 2017, e20163518; DOI:10.1542/peds.2016-3518.

Kaelber DC, Liu W, Ross M, et al. Diagnosis and Medication Treatment of Pediatric Hypertension: A Retrospective Cohort Study. Pediatrics. 2016; 138(6): e20162195; DOI: 10.1542/peds.2016-2195.

Fiks AG, Ross, ME, Mayne SL, et al. Preschool ADHD Diagnosis and Stimulant Use Before and After the 2011 AAP Practice Guideline.Pediatrics. 2016; 38 (6): e20162025; DOI: 10.1542/peds.2016-2025.

Mayne SL, Ross ME, Song L, et al. Variations in mental health diagnosis and prescribing across pediatric primary care practices. Pediatrics. 2016;137(5):e20152974. doi: 10.1542/peds.2015-2974.

Fiks AG, Grundmeier RW, Steffes J, Adams WG, Kaelber DC, Pace WD, & Wasserman RC (2015). Comparative Effectiveness Research Through a Collaborative Electronic Reporting Consortium. Pediatrics, 136(1), e215-e224.

Fiks AG, Mayne SL, Song L, Steffes J, Liu W, McCarn B, Margolis B, Grimes A, Gotleib E, Localio R, Ross ME, Grundmeier RW, Wasserman R, Leslie LK. Changing patterns of alpha agonist medication use in children 2009-2011. Journal of Child and Adolescent Psychopharmacology, 2015;25(4):362-367. doi:10.1089/cap.2014.0122

Grundmeier R, Song L, Ramos M, Fiks A, Elliott M, Fremont A, Pace W, Wasserman R, Localio R. Imputing missing race/ethnicity in pediatric electronic health records: reducing bias with use of the US Census location and surname data. Health Services Research. 2015;50(4):946-960. doi: 10.1111/1475-6773.12295

Miller D, Noonan K, Fiks AG, Lehmann CU. Increasing pediatrician participation in EHR incentive programs.Pediatrics. 2015; 135(1):e1-4. doi: 10.1542/peds.2014-2438.

Fiks AG, Grundmeier RW. Elucidating Challenges and Opportunities in the Transition to ICD-10-CM.Pediatrics. July 1, 2014 2014;134(1):169-170.

Presentations

Kaelber, D, “Researching the Cosmos: the Journey to Cosmos Data Submission.” Epic XGM Research Advisory Council, Verona, WI, May, 2019.

Kaelber, D, “Putting the Hypertension Clinical Practice Guideline into Action: A Workshop for Primary Care Providers” IPHA workshop. Pediatric Academic Societies Meting April 2019, Baltimore, MD.

Kaelber, D, “Researching the Cosmos: the Journey to Cosmos Data Submission.” Epic XGM Research Advisory Council, Verona, WI, May, 2019.

Fiks AG, “What Technology Can (and Can’t) Do for Pediatric Primary Care,” Pediatric Grand Rounds at Robert Wood Johnson Medical School, New Brunswick, New Jersey, February 2018.

Fiks, A. “Comparative Effectiveness Research Through Collaborative Electronic Reporting: Methods and Findings to Improve Pediatric Care” Health Resources and Services Administration, Maternal and Child Health Bureau (HRSA MCHB), November 2017.

Fiks, A. "How to Raise HPV Vaccination Rates: From Evidence to Action". Centers for Disease Control and Prevention and Academic Pediatric Association Sponsored Pediatric Grand Rounds, University of Virginia, Charlottesville, VA, January. 2017.

Fiks, A. “What Health Information Technology Can (and Can’t) Do for Pediatric Care”. Pediatric Grand Rounds, The Children’s Hospital of Philadelphia, Philadelphia, PA. October, 2016.

Fiks, A. "Testing a Pediatrician-delivered Guidelines-based Social Media Intervention". Pediatrics 21 Plenary Presentation, American Academy of Pediatrics National Conference and Exhibition, San Francisco, CA. October, 2016.

Fiks, A. Using EHR Data to Conduct PBRN Research, presented at the 2016 NAPCRG Practice-Based Research Network Conference. Bethesda, MD. July 12, 2016.

Fiks, Alex. Keynote Presentation. "The Comparative Effectiveness Research through Collaborative Electronic Reporting Consortium: Using Pediatric Electronic Health Records to Address Medication Use, Safety, and Efficacy." The Tenth Annual Chapel Hill Pharmaceutical Sciences Conference. UNC Eshelman School of Pharmacy. Chapel Hill, NC. May 13, 2016.

Grundmeier, R. "EnRICH Webinar on Secondary Use of Electronic Health Data for Child Health Research: Opportunities and Challenges." EnRICH webinars are conducted by the MCH Training and Research Resource Center, which is funded by the Maternal and Child Health Bureau (MCHB), Office of Epidemiology and Research (OER), Division of Research (DoR). May 5, 2016.

Daymont C, Ross, ME, Grundmeier R, Fiks AG, Wasserman RC, Localio A. Validation of Method to Prepare Electronic Health Record Growth Data for Analysis. Presented as a poster presentation at the Pediatric Academic Societies Annual Meeting, Baltimore, Maryland. May 1, 2016.

Fiks, Alex. "CER²: Comparative Effectiveness Research through Collaborative Electronic Reporting," Invited Lecture as part of the Pediatric Pharmaceutical Safety Databases Topic Symposium at the Pediatric Academic Societies Annual Meeting. Baltimore, Maryland. May 1, 2016.

Wasserman, Richard. "Pediatric pharmaceutical safety database research of the future: what's needed?" Invited Lecture as part of the Pediatric Pharmaceutical Safety Databases Topic Symposium at the Pediatric Academic Societies Annual Meeting, Baltimore, Maryland. 5/1/16

Fiks, Alex. "Meaningfully Engaging Families in Care Using Patient Portal: The Good, the Bad, and the Future," Invited Lecture at the Medical Informatics Special Interest Group at the Pediatric Academic Societies Annual Meeting, Baltimore, Maryland. 4/30/16

Fiks, Alex. Primary Care Practice-Based Research on Children's Behavioral Health: Methods and Insights for Practice and Policy. Center for Mental Health Policy and Services Research. University of Pennsylvania. Philadelphia, PA. March 8, 2016.

Fiks, Alex. Title: Comparative Effectiveness Research through Collaborative Electronic Reporting: Methods and Findings to Improve Pediatric Care. 2016 DCRI & Pediatrics Research Day. Medical University of South Carolina. Charleston, SC. March 3, 2016.

Grundmeier R. Clinical Informatics and Child Health Discovery: Tales from CHOP and the CER² Consortium, Presentation at Rady Children's Hospital San Diego

Grundmeier R. Pediatric Biomedical Informatics: A Modern Journey to Improve Child Health, Keynote Address at the 2014 Ed Quigley Clinical Research Symposium Rady Children's Hospital San Diego

Comparative Effectiveness Research through Collaborative Electronic Reporting (CER²): A Network of Pediatric EHR-Based Research Networks; Pediatric Health Care Variation Research Collaborative Conference.

Fiks A, Grundmeier R, Song L, Steffes J, McCarn B, Margolis B, Mayne S, Localio R, Wasserman R. Psychopharmacology in Pediatric Primary Care: An ePROS Study of Electronic Health Records. Presented as a poster at 2013 Pediatric Academic Societies' Annual Meeting.

Grundmeier R, Song L, Ramos, Fiks A, Elliott M, Fremont A, Wasserman R, Localio R. Imputing Race and Ethnicity for Healthcare Disparities Research. Presented as a platform at 2013 Pediatric Academic Societies' Annual Meeting.

Daymont C, Fiks A, Grundmeier RW. An Automated Method for Cleaning Growth Measurements in Large Datasets. Presented as a poster at 2014 Pediatric Academic Societies' Annual Meeting.

Fiks A, Liu W, Steffes J, Song L, McCarn B, Margolis B, Mayne S, Grimes A, Localio R, Ross M, Gotlieb E, Wasserman R, Grundmeier R. Real-World Impact of Stimulant Medication on Weight, Height, & BMI: An EHR-Based Analysis from PeRC & ePROS. Presented as a platform at 2014 Pediatric Academic Societies' Annual Meeting

Grundmeier R, Liu W, Steffes J, McCarn B, Localio R, Song L, Mayne S, Ross M, Grimes A, Gotlieb E, Margolis B, Wasserman R, Fiks A. Real-World Impact of Atypical Antipsychotics on Growth: A PeRC & ePROS Study. Presented as a poster at 2014 Pediatric Academic Societies' Annual Meeting

Fiks A, Song L, Steffes J, Liu W, McCarn B, Mayne S, Margolis B, Grimes A, Gotlieb E, Localio R, Ross M, Wasserman R, Grundmeier R. Changing Patterns of Alpha Agonist Medication Use in Children, 2009-2011. Presented as a poster at 2014 Pediatric Academic Societies' Annual Meeting

Grundmeier R, Song L, Liu W, McCarn B, Steffes J, Ross M, Localio A, Margolis B, Gotlieb E, Grimes A, Wasserman R, Fiks A. Psychopharmacological Treatments and Behavioral Health Co-morbidities Experienced by Children with Sleep Disturbances: An ePROS and PeRC Study. Presented as a poster at 2014 Pediatric Academic Societies' Annual Meeting

Margolis B., Grundmeier R, Liu W, Steffes J, McCarn B, Localio R, Song L, Mayne S, Ross M, Grimes A, Gotlieb E, Wasserman R, Fiks A. Assessing the Effects of Atypical Antipsychotics on the Weight, Height, and BMI of Children in Pediatric Primary Care. Presented at 2014 Child Health Services Research Interest Group Meeting

Wasserman, R. Pitfalls and Realities of Working with Big Data: Reflections of a PBRN "Big Data" Newbie. Presented at 2014 North American Primary Care Research Group Annual Meeting

Steffes J, Wasserman R, Liu W, Song L, McCarn B, Localio R, Fiks A, Slora E, Grundmeier R. Electronic Health Record (EHR) Investigation of Pediatric Obesity: No Easy Insights. Presented as a poster at 2013 Pediatric Academic Societies' Annual Meeting

Fiks AG, "Pharmacoepidemiology," American Academy of Pediatrics: Pediatric Research in Office Settings (PROS) Chapter Coordinators Meeting, New Orleans, LA

Wasserman RC & Fiks AG, "Update on Comparative Effectiveness Research through Collaborative Electronic Reporting (CER²)," American Academy of Pediatrics: Pediatric Research in Office Settings (PROS) Chapter Coordinators Meeting, New Orleans, LA

Wasserman RW, Fiks AG, "e-Practice-Based Research Networks," Invited Lecture at North Shore University Health System (University of Chicago), Evanston, IL

"The Care Assistant," Invited Panelist, Health Information Technology Conference, The Science Center, Philadelphia, PA

"Update on Comparative Effectiveness Research through Collaborative Electronic Reporting (CER²)," American Academy of Pediatrics: Pediatric Research in Office Settings (PROS) Chapter Coordinators Meeting, Des Plaines, IL

Wasserman RC, "Secondary use of Primary Care EHR Data: Extracting from Multiple Implementations of Multiple Vendor Products," 2013 Philadelphia Health Informatics Symposium, Philadelphia, Pennsylvania.

Wasserman RC, "Developing a National EHR Initiative in Pediatrics," North American Primary Care Research Group Practice-Based Research Network meeting, Bethesda, MD

Margolis B, Fiks AG, Grundmeier R, Song L, Steffes J, McCarn B, Mayne S, Localio R, Wasserman RC, "Diverse Patterns of Psychotropic Medication Usage in Pediatric Primary Care," Podium Presentation at the Academy Health 2013 Child Health Services Research Interest Group Meeting, Baltimore, MD

Last Updated

08/01/2023

Source

American Academy of Pediatrics